The TYPO3 core team has just released TYPO3 version 4.3.3, which is now ready for you to download. It is a maintenance release of the current stable branch 4.3 and contains bugfixes and security fixes.
IMPORTANT: This version includes important security fixes to the TYPO3 core. A security announcement has just been released:
http://typo3.org/teams/security/security-bulletins/typo3-sa-2010-008/
For details about the release, see:
http://wiki.typo3.org/index.php/TYPO3_4.3.3
Don't people just get tired of constant upgrades? I mean.. fixing security issues is an important thing, but a new release every 2 months? It can become very tiresome for the user, especially if you have half a dozen sites that need to be upgraded.
I'm not sure there's much they can do about it, with hackers finding security holes every minute of every day. It is a pain in the butt however, software and bugs go together, as does security patches and hackers.
Factor in the cost of updating I guess for your clients, as it's just a necessary part of using a cms, and at least they'll know that you're watching their backs.