Dzoic Handshakes has been around since 2005 and offers a really attractive interface with a good, solid, support structure. As a bonus, their code is open sourced (but the product itself is not free).
I’ve tested this software out but not had a chance to write a review as of yet. I do think it’s great software and hopefully, from their demo on the website, you’ll think so too!
Dzoic Handshakes comes in two different price packages, you can purchase it directly or you can lease it for $25 / month.